Ozone therapy in 65 patients with fibromyalgia



Fibromyalgia is a persistent dysfunction with a really complicated symptomatology. Though generalized extreme ache is taken into account to be the cardinal symptom of the illness, many different related signs, particularly non-restorative sleep, persistent fatigue, nervousness, and depressive signs additionally play a related position within the diploma of incapacity attribute of the illness. Ozone remedy, which is used to deal with a variety of illnesses and appears to be significantly helpful within the remedy of many persistent illnesses, is believed to behave by exerting a light, transient, and managed oxidative stress that promotes an up-regulation of the antioxidant system and a modulation of the immune system. In line with these mechanisms of motion, it was hypothesized that ozono generatoriai remedy could possibly be helpful in fibromyalgia administration, the place the employed therapies are fairly often ineffective.


Sixty-five sufferers with fibromyalgia, in response to the definition of the American Faculty of Rheumatology (Arthritis Rheum 1990; 33: 160-172), have been handled on the MEDE Clinic (Sacile, Pordenone, Italy) from February 2016 to October 2018. Females have been 55 and males have been 10; age ranged from 30 to 72 years, and the time from fibromyalgia prognosis ranged from zero.5 to 33 years. Therapy was made by autohemotransfusion in 55 sufferers and by ozone rectal insufflations in 10 sufferers, in response to SIOOT (Scientific Society of Oxygen Ozone Remedy) protocols, twice every week for one month after which twice a month as upkeep remedy.


We discovered a significative enchancment (>50% of signs) in 45 sufferers (70%). No affected person reported essential negative effects. In conclusion, at our information, that is the most important examine of sufferers with fibromyalgia handled with ozone remedy reported within the literature and it demonstrates that the ozone remedy is an efficient remedy for fibromyalgia sufferers with out important negative effects.


In the intervening time, ozone remedy appears a remedy that, additionally as a result of with none facet impact, is feasible to be proposed to sufferers with fibromyalgia that aren’t acquiring enough outcomes from different accessible remedies and it may be thought of as complementary/integrative medication.

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